Sensitive

Late-onset Alzheimer's disease

SLC10A2 · rs16961023

Where this position leads

Condition: Alzheimer's Disease

rs16961023 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs16961023 rs16961023 SLC10A2

What the study found

Who was studied 1,825 African American ancestry cases, 3,784 African American ancestry controls.

The effect Each copy of the C allele shifted the measure 0.41 lower (95% confidence interval 0.27-0.55); p = 5 × 10−8.

How common The C allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 13, band 13q33.1 — between genes, 32.4 kb from SLC10A2.

What each result means

C/C Two copies of the version the research linked to Late-onset Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Late-onset Alzheimer's disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Late-onset Alzheimer's disease. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs16961023

What is rs16961023?

rs16961023 is a single position in the genome, in or near the SLC10A2 gene. Published research associates it with late-onset alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16961023 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs16961023?

Subjects that appear in the title or abstract of the same papers as this rsID include learning and focus (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs16961023 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16961023 come from?

GWAS Catalog, Alzheimers Dement 2016, PMID:27770636. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Late-onset Alzheimer's disease (rs16961023). MyGeneLog™. https://www.mygenelog.com/variants/rs16961023

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