A/APublished research associates this genotype with typical/baseline likelihood of Exfoliation glaucoma or exfoliation syndrome — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Exfoliation glaucoma or exfoliation syndrome.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Exfoliation glaucoma or exfoliation syndrome compared to the general population.
Scientific reports · 2014 · PMID 24938310 · open access
Questions about rs16958445
What is rs16958445?
rs16958445 is a single position in the genome, in or near the TBC1D21 gene. Published research associates it with exfoliation glaucoma or exfoliation syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs16958445 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs16958445 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16958445 come from?
GWAS Catalog, Sci Rep 2014, PMID:24938310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.