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Intelligence

SKAP1 · rs16954078

Where this position leads

Condition: Intelligence

rs16954078 Condition: Intelligence Intelligence Condition rs16954078 rs16954078 SKAP1

What the study found

Who was studied up to 58,799 European ancestry adults, up to 19,509 European ancestry children.

The effect Each copy of the A allele shifted the measure 5.55 z score lower; p = 3 × 10−8.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in an intron of SKAP1.

What each result means

A/A Two copies of the version the research linked to Intelligence. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Intelligence. That is a smaller link than two copies.
T/T No copy of the version the research linked to Intelligence. This is the starting point the study compared everyone against.
Source

Questions about rs16954078

What is rs16954078?

rs16954078 is a single position in the genome, in or near the SKAP1 gene. Published research associates it with intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16954078 linked to?

On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.

Does having rs16954078 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16954078 come from?

GWAS Catalog, Nature genetics 2017, PMID:28530673. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intelligence (rs16954078). MyGeneLog™. https://www.mygenelog.com/variants/rs16954078

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