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Total protein levels (UKB data field 30860)

NCOA2 · rs16936880

Where this position leads

Condition: Celiac Disease

rs16936880 Condition: Celiac Disease Celiac Disease Condition rs16936880 rs16936880 NCOA2

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0224 lower (95% confidence interval 0.016-0.029); p = 6 × 10−12.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 8, band 8q13.3 — in an intron of NCOA2.

What each result means

C/C No copy of the version the research linked to Total protein levels (UKB data field 30860). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total protein levels (UKB data field 30860). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total protein levels (UKB data field 30860). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16936880

What is rs16936880?

rs16936880 is a single position in the genome, in or near the NCOA2 gene. Published research associates it with total protein levels (ukb data field 30860). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16936880 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs16936880 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16936880 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total protein levels (UKB data field 30860) (rs16936880). MyGeneLog™. https://www.mygenelog.com/variants/rs16936880

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