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Serum amyloid A-1 protein levels

LDHC · rs16935432

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.515 higher (95% confidence interval 0.4-0.63); p = 2 × 10−17.

Where it sits Chromosome 11, band 11p15.1 — in an intron of LDHC.

What each result means

A/A Two copies of the version the research linked to Serum amyloid A-1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum amyloid A-1 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum amyloid A-1 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs16935432

What is rs16935432?

rs16935432 is a single position in the genome, in or near the LDHC gene. Published research associates it with serum amyloid a-1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16935432 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16935432 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum amyloid A-1 protein levels (rs16935432). MyGeneLog™. https://www.mygenelog.com/variants/rs16935432

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