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Who was studied 434,794 European ancestry female individuals.
The effect
Each copy of the C allele shifted the measure 0.0234 higher (95% confidence interval 0.017-0.03); p = 2 × 10−13.
How common The C allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — in an intron of SOX5.
What each result means
C/CTwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs16926778
What is rs16926778?
rs16926778 is a single position in the genome, in or near the SOX5 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs16926778 linked to?
On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs16926778 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16926778 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 30322171239Reads by AI crawlersClaude3ChatGPT2Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others9Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Body mass index (rs16926778). MyGeneLog™. https://www.mygenelog.com/variants/rs16926778