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Bilirubin levels

SLCO1A2 · rs16923647

What the study found

Who was studied 38,000 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.154 higher (95% confidence interval 0.13-0.18); p = 4 × 10−28.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1A2.

What each result means

C/C No copy of the version the research linked to Bilirubin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Bilirubin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16923647

What is rs16923647?

rs16923647 is a single position in the genome, in or near the SLCO1A2 gene. Published research associates it with bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16923647 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16923647 come from?

GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bilirubin levels (rs16923647). MyGeneLog™. https://www.mygenelog.com/variants/rs16923647

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