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Body mass index

BDNF · rs16917237

Where this position leads

Condition: Obesity and Body Weight

rs16917237 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs16917237 rs16917237 BDNF

What the study found

Who was studied up to 309,889 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0409 lower (95% confidence interval -); p = 1 × 10−34.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 11, band 11p14.1 — in an intron of BDNF-AS.

What each result means

G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16917237

What is rs16917237?

rs16917237 is a single position in the genome, in or near the BDNF gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16917237 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs16917237 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16917237 come from?

GWAS Catalog, PLoS Genet 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs16917237). MyGeneLog™. https://www.mygenelog.com/variants/rs16917237

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