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Triglyceride levels (MTAG)

DOCK7 · rs1690761

What the study found

Who was studied 361,194 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0774 higher (95% confidence interval 0.072-0.082); p = 4 × 10−196.

Where it sits Chromosome 1, band 1p31.3 — in an intron of DOCK7.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Triglyceride levels (MTAG) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglyceride levels (MTAG).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglyceride levels (MTAG) compared to the general population.
Source

Questions about rs1690761

What is rs1690761?

rs1690761 is a single position in the genome, in or near the DOCK7 gene. Published research associates it with triglyceride levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1690761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1690761 come from?

GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (MTAG) (rs1690761). MyGeneLog™. https://www.mygenelog.com/variants/rs1690761

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