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Retinal thickness (pixel 118_35)

near ASB7 · rs1689939

What the study found

Who was studied 43,148 European ancestry individuals; replicated in 1,179 Central or South Asian individuals, 1,161 African ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.22 higher (95% confidence interval 0.17-0.27); p = 9 × 10−18.

How common The C allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 15, band 15q26.3 — between genes, 13.3 kb from ASB7.

What each result means

C/C Two copies of the version the research linked to Retinal thickness (pixel 118_35). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Retinal thickness (pixel 118_35). That is a smaller link than two copies.
T/T No copy of the version the research linked to Retinal thickness (pixel 118_35). This is the starting point the study compared everyone against.
Source

Questions about rs1689939

What is rs1689939?

rs1689939 is a single position in the genome, in or near the near ASB7 gene. Published research associates it with retinal thickness (pixel 118_35). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1689939 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1689939 come from?

GWAS Catalog, Nature communications 2025, PMID:39904976. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Retinal thickness (pixel 118_35) (rs1689939). MyGeneLog™. https://www.mygenelog.com/variants/rs1689939

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