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Ankylosing spondylitis

near ZKSCAN8P2 · rs16893761

Where this position leads

Condition: Ankylosing Spondylitis

rs16893761 Condition: Ankylosing Spondylitis Ankylosing Spondylitis Condition rs16893761 rs16893761 near ZKSCAN8…

What the study found

Who was studied 7,551 European ancestry cases, 1,258,581 European ancestry controls.

The effect Each copy of the G allele shifted the measure 1.1 higher (95% confidence interval 1.04-1.16); p = 1 × 10−300.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — between genes, 0.1 kb from ZKSCAN8P2.

What each result means

A/A No copy of the version the research linked to Ankylosing spondylitis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Ankylosing spondylitis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Ankylosing spondylitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16893761

What is rs16893761?

rs16893761 is a single position in the genome, in or near the near ZKSCAN8P2 gene. Published research associates it with ankylosing spondylitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16893761 linked to?

On MyGeneLog this position is linked to Ankylosing Spondylitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs16893761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16893761 come from?

GWAS Catalog, Frontiers in immunology 2026, PMID:42305533. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ankylosing spondylitis (rs16893761). MyGeneLog™. https://www.mygenelog.com/variants/rs16893761

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