Sensitive

Colorectal cancer

EIF3H · rs16892766

Where this position leads

Condition: Colorectal Cancer

rs16892766 Condition: Colorectal Cancer Colorectal Cancer Condition rs16892766 rs16892766 EIF3H

What the study found

Who was studied 922 European ancestry cases, 927 European ancestry controls; replicated in 17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls.

The effect Each copy of the A allele carried 1.27 times the odds of Colorectal cancer (95% confidence interval 1.20-1.34); p = 3 × 10−18.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 8, band 8q23.3 — between genes, 3.3 kb from LOC105375712.

What each result means

A/A Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
C/C No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Source

Questions about rs16892766

What is rs16892766?

rs16892766 is a single position in the genome, in or near the EIF3H gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16892766 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs16892766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16892766 come from?

GWAS Catalog, Nat Genet 2008, PMID:18372905. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs16892766). MyGeneLog™. https://www.mygenelog.com/variants/rs16892766

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