Standard

Creatinine levels

ARL15 · rs16882647

Where this position leads

Condition: Kidney Function

rs16882647 Condition: Kidney Function Kidney Function Condition rs16882647 rs16882647 ARL15

What the study found

Who was studied 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0296 lower (95% confidence interval 0.021-0.039); p = 2 × 10−10.

Where it sits Chromosome 5, band 5q11.2 — in an intron of ARL15.

What each result means

A/A No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16882647

What is rs16882647?

rs16882647 is a single position in the genome, in or near the ARL15 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16882647 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs16882647 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16882647 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Creatinine levels (rs16882647). MyGeneLog™. https://www.mygenelog.com/variants/rs16882647

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