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High fluorescence immature platelet fraction

TLK1 · rs16859087

What the study found

Who was studied 36,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0831 SD units lower (95% confidence interval 0.057-0.109); p = 5 × 10−10.

How common The A allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 2, band 2q31.1 — in an intron of TLK1.

What each result means

A/A Two copies of the version the research linked to High fluorescence immature platelet fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to High fluorescence immature platelet fraction. That is a smaller link than two copies.
G/G No copy of the version the research linked to High fluorescence immature platelet fraction. This is the starting point the study compared everyone against.
Source

Questions about rs16859087

What is rs16859087?

rs16859087 is a single position in the genome, in or near the TLK1 gene. Published research associates it with high fluorescence immature platelet fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16859087 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16859087 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High fluorescence immature platelet fraction (rs16859087). MyGeneLog™. https://www.mygenelog.com/variants/rs16859087

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