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Who was studied 9,304 African or African American cases, 19,024 African or African American controls.
The effect
Each copy of the A allele carried 1.19 times the odds of Breast cancer (estrogen-receptor positive) (95% confidence interval 1.13-1.26); p = 7 × 10−10.
How common The A allele had a frequency of about 85% in the people studied.
Where it sits Chromosome 2, band 2q35 — in an intron of TESHL.
What each result means
A/ATwo copies of the version the research linked to Breast cancer (estrogen-receptor positive). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Breast cancer (estrogen-receptor positive). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Breast cancer (estrogen-receptor positive). This is the starting point the study compared everyone against.
rs16856925 is a single position in the genome, in or near the TESHL gene. Published research associates it with breast cancer (estrogen-receptor positive). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs16856925 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs16856925 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16856925 come from?
GWAS Catalog, Nature genetics 2024, PMID:38741014. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Breast cancer (estrogen-receptor positive) (rs16856925). MyGeneLog™. https://www.mygenelog.com/variants/rs16856925