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Immune reponse to smallpox (secreted IL-1beta)

EPGN · rs16850885

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Immune reponse to smallpox (secreted IL-1beta) compared to the general population. (GWAS Catalog, Hum Genet 2012, PMID:22610502)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Immune reponse to smallpox (secreted IL-1beta). (GWAS Catalog, Hum Genet 2012, PMID:22610502)
G/G Published research associates this genotype with typical/baseline likelihood of Immune reponse to smallpox (secreted IL-1beta) — no copies of the reported risk allele. (GWAS Catalog, Hum Genet 2012, PMID:22610502)

Source: GWAS Catalog, Hum Genet 2012, PMID:22610502

Questions about rs16850885

What is rs16850885?

rs16850885 is a single position in the genome, in or near the EPGN gene. Published research associates it with immune reponse to smallpox (secreted il-1beta). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16850885 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16850885 come from?

GWAS Catalog, Hum Genet 2012, PMID:22610502. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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