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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 430,445 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0182 higher (95% confidence interval 0.013-0.024); p = 4 × 10−11.
How common The G allele had a frequency of about 79% in the people studied.
Where it sits Chromosome 1, band 1q42.13 — in an intron of COQ8A.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Highest math class taken — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Highest math class taken.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Highest math class taken compared to the general population.
rs16846735 is a single position in the genome, in or near the COQ8A gene. Published research associates it with highest math class taken. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs16846735 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16846735 come from?
GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Highest math class taken (rs16846735). MyGeneLog™. https://www.mygenelog.com/variants/rs16846735