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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 408,112 British individuals.
The effect
Each copy of the T allele shifted the measure 0.0178 lower (95% confidence interval 0.013-0.023); p = 4 × 10−11.
How common The T allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 1, band 1q31.3 — in an intron of DENND1B.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Lymphocyte count — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lymphocyte count.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lymphocyte count compared to the general population.
rs16841904 is a single position in the genome, in or near the DENND1B gene. Published research associates it with lymphocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs16841904 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16841904 come from?
GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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