Standard

Lung function (FEV1) and waist circumference adjusted for BMI

near DIS3L2 · rs16828537

Where this position leads

Condition: Waist Circumference

rs16828537 Condition: Waist Circumference Waist Circumference Condition rs16828537 rs16828537 near DIS3L2

What the study found

Who was studied up to 100,285 Chinese ancestry individuals; replicated in up to 457,756 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 4 × 10−19.

Where it sits Chromosome 2, band 2q37.1 — between genes, 14.3 kb from DIS3L2.

What each result means

A/A Two copies of the version the research linked to Lung function (FEV1) and waist circumference adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lung function (FEV1) and waist circumference adjusted for BMI. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lung function (FEV1) and waist circumference adjusted for BMI. This is the starting point the study compared everyone against.
Source

Questions about rs16828537

What is rs16828537?

rs16828537 is a single position in the genome, in or near the near DIS3L2 gene. Published research associates it with lung function (fev1) and waist circumference adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16828537 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs16828537 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16828537 come from?

GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung function (FEV1) and waist circumference adjusted for BMI (rs16828537). MyGeneLog™. https://www.mygenelog.com/variants/rs16828537

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