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Estimated glomerular filtration rate (creatinine)

ARMC9 · rs16827879

What the study found

Who was studied 1,004,040 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals, 2 individuals; replicated in 417,288 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.00176 lower (95% confidence interval 0.0012-0.0023); p = 5 × 10−11.

How common The T allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 2, band 2q37.1 — in an intron of ARMC9.

What each result means

C/C No copy of the version the research linked to Estimated glomerular filtration rate (creatinine). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Estimated glomerular filtration rate (creatinine). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate (creatinine). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16827879

What is rs16827879?

rs16827879 is a single position in the genome, in or near the ARMC9 gene. Published research associates it with estimated glomerular filtration rate (creatinine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16827879 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16827879 come from?

GWAS Catalog, Nature communications 2021, PMID:34272381. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate (creatinine) (rs16827879). MyGeneLog™. https://www.mygenelog.com/variants/rs16827879

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