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Hypothyroidism

MIR3681HG · rs16799

Where this position leads

Condition: Hypothyroidism

rs16799 Condition: Hypothyroidism Hypothyroidism Condition rs16799 rs16799 MIR3681HG

What the study found

Who was studied 58,783 European ancestry cases, 633,203 European ancestry controls.

The effect Each copy of the C allele carried 1.08 times the odds of Hypothyroidism (95% confidence interval 1.07-1.1); p = 2 × 10−22.

Where it sits Chromosome 2, band 2p24.3 — in an intron of MIR3681HG.

What each result means

C/C Two copies of the version the research linked to Hypothyroidism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hypothyroidism. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hypothyroidism. This is the starting point the study compared everyone against.
Source

Questions about rs16799

What is rs16799?

rs16799 is a single position in the genome, in or near the MIR3681HG gene. Published research associates it with hypothyroidism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16799 linked to?

On MyGeneLog this position is linked to Hypothyroidism. The research behind each link, and its sources, are set out on that condition page.

Does having rs16799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16799 come from?

GWAS Catalog, European journal of endocrinology 2024, PMID:39067062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hypothyroidism (rs16799). MyGeneLog™. https://www.mygenelog.com/variants/rs16799

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