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Who was studied 797 European ancestry cases, 140,558 European ancestry controls; replicated in 2,812 European ancestry cases, 229,788 European ancestry controls.
The effect
Each copy of the G allele carried 0.81 times the odds of Polycystic ovary syndrome (adjusted for age) (95% confidence interval 0.76–0.87] ); p = 1 × 10−8.
How common The G allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 11, band 11q23.2 — in an intron of ZBTB16.
What each result means
A/ANo copy of the version the research linked to Polycystic ovary syndrome (adjusted for age). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Polycystic ovary syndrome (adjusted for age). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Polycystic ovary syndrome (adjusted for age). That is the strongest link of the three results. A link in a study is not a diagnosis.
Human reproduction (Oxford, England) · 2022 · PMID 34791234 · open access
Questions about rs1672716
What is rs1672716?
rs1672716 is a single position in the genome, in or near the ZBTB16 gene. Published research associates it with polycystic ovary syndrome (adjusted for age). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1672716 linked to?
On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs1672716 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1672716 come from?
GWAS Catalog, Hum Reprod 2021, PMID:34791234. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 3828224218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total38Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Polycystic ovary syndrome (adjusted for age) (rs1672716). MyGeneLog™. https://www.mygenelog.com/variants/rs1672716