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Who was studied 12,074 European, African, Admixed American, Asian or unknown ancestry cases, 15,833 European, African, Admixed American, Asian or unknown ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 1 × 10−14.
Where it sits Chromosome 19, band 19q13.32 — in an intron of LNCOB1.
What each result means
A/ANo copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025 · PMID 39998322 · open access
Questions about rs166907
What is rs166907?
rs166907 is a single position in the genome, in or near the LNCOB1 gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs166907 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE). The research behind each link, and its sources, are set out on that condition page.
Does having rs166907 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs166907 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2025, PMID:39998322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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