Standard
Gut microbiota (functional units)
SEMA5A · rs1666789
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gut microbiota (functional units) compared to the general population.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gut microbiota (functional units).
T/T
Published research associates this genotype with typical/baseline likelihood of Gut microbiota (functional units) — no copies of the reported risk allele.
Source
The effect of host genetics on the gut microbiome
Bonder MJ,
Kurilshikov A,
Tigchelaar EF,
Mujagic Z,
Imhann F,
Vila AV,
Deelen P,
Vatanen T,
Schirmer M,
Smeekens SP,
Zhernakova DV,
Jankipersadsing SA
and 18 more — show all
Jaeger M,
Oosting M,
Cenit MC,
Masclee AA,
Swertz MA,
Li Y,
Kumar V,
Joosten L,
Harmsen H,
Weersma RK,
Franke L,
Hofker MH,
Xavier RJ,
Jonkers D,
Netea MG,
Wijmenga C,
Fu J,
Zhernakova A
Nature genetics · 2016 · PMID 27694959
Questions about rs1666789
What is rs1666789?
rs1666789 is a single position in the genome, in or near the SEMA5A gene. Published research associates it with gut microbiota (functional units). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1666789 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1666789 come from?
GWAS Catalog, Nat Genet 2016, PMID:27694959. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants