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Who was studied 19,901 Finnish ancestry cases, 199,208 Finnish ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 7 × 10−15.
How common The C allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 10, band 10p14 — between genes, 40.7 kb from LINC02676.
What each result means
C/CTwo copies of the version the research linked to Chronic inflammatory sinonasal disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Chronic inflammatory sinonasal disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Chronic inflammatory sinonasal disease. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 36653354 · open access
Questions about rs1663680
What is rs1663680?
rs1663680 is a single position in the genome, in or near the near LINC02676 gene. Published research associates it with chronic inflammatory sinonasal disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1663680 linked to?
On MyGeneLog this position is linked to Chronic Inflammatory Sinonasal Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1663680 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1663680 come from?
GWAS Catalog, Nature communications 2023, PMID:36653354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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