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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,560 European ancestry female individuals, 4,997 European ancestry male individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−8.
How common The A allele had a frequency of about 92% in the people studied.
Where it sits Chromosome 2, band 2p11.2 — between genes, 4.3 kb from MRPL45P1.
What each result means
A/ATwo copies of the version the research linked to Visceral fat. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Visceral fat. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Visceral fat. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1659258
What is rs1659258?
rs1659258 is a single position in the genome, in or near the THNSL2 gene. Published research associates it with visceral fat. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs1659258?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1659258 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1659258 come from?
GWAS Catalog, PLoS Genet 2012, PMID:22589738. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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