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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
1 / 4
Its strongest genetic-study result is p = 10−14, with 1 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 2,440 African American or Afro-Caribbean cases, 53,065 African American or Afro-Caribbean controls, 26,295 European ancestry cases, 289,373 European ancestry controls, 2,018 Hispanic or Latin American cases, 27,296 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 0.114 higher (95% confidence interval 0.082-0.145); p = 5 × 10−15.
How common The T allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — in an intron of POLR1HASP.
What each result means
C/CNo copy of the version the research linked to Takes medication for Thyroid problems?. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Takes medication for Thyroid problems?. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Takes medication for Thyroid problems?. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs1655907
What is rs1655907?
rs1655907 is a single position in the genome, in or near the POLR1HASP gene. Published research associates it with takes medication for thyroid problems?. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1655907 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1655907 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license
Takes medication for Thyroid problems? (rs1655907). MyGeneLog™. https://www.mygenelog.com/variants/rs1655907