NLRC5 · rs1651663
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 122,644 European ancestry individuals (MTAG effective sample size boosted by proton density fat fraction samples).
The effect Each copy of the A allele shifted the measure 0.028 lower (95% confidence interval 0.019-0.037); p = 3 × 10−10.
How common The A allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 16, band 16q13 — in an intron of NLRC5.
rs1651663 is a single position in the genome, in or near the NLRC5 gene. Published research associates it with metabolic dysfunction-associated steatotic liver disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science advances 2026, PMID:41686896. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Metabolic dysfunction-associated steatotic liver disease (MTAG) (rs1651663). MyGeneLog™. https://www.mygenelog.com/variants/rs1651663