C/CPublished research associates this genotype with typical/baseline likelihood of Venous thromboembolism — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Venous thromboembolism.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Venous thromboembolism compared to the general population.
rs1649936 is a single position in the genome, in or near the NRG3 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1649936 linked to?
On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs1649936 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1649936 come from?
GWAS Catalog, Thromb Haemost 2021, PMID:33592630. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.