Standard

Sequestosome-1 (analyte X7695.106) levels

near GPNMB · rs1637190

What the study found

Who was studied 3,334 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.173 lower (95% confidence interval 0.13-0.22); p = 1 × 10−11.

How common The G allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 7, band 7p15.3 — between genes, 6.5 kb from GPNMB.

What each result means

A/A No copy of the version the research linked to Sequestosome-1 (analyte X7695.106) levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Sequestosome-1 (analyte X7695.106) levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Sequestosome-1 (analyte X7695.106) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1637190

What is rs1637190?

rs1637190 is a single position in the genome, in or near the near GPNMB gene. Published research associates it with sequestosome-1 (analyte x7695.106) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1637190 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1637190 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sequestosome-1 (analyte X7695.106) levels (rs1637190). MyGeneLog™. https://www.mygenelog.com/variants/rs1637190

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