Left eye retinal fundus image self-supervised embedding endophenotype 116
HERC2 · rs1635166
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 65,087 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 6.1 lower (95% confidence interval 4.63-7.56); p = 4 × 10−16.
How common The C allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 15, band 15q13.1 — in an intron of HERC2.
What each result means
C/CTwo copies of the version the research linked to Left eye retinal fundus image self-supervised embedding endophenotype 116. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Left eye retinal fundus image self-supervised embedding endophenotype 116. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Left eye retinal fundus image self-supervised embedding endophenotype 116. This is the starting point the study compared everyone against.
PLoS genetics · 2024 · PMID 38728357 · open access
Questions about rs1635166
What is rs1635166?
rs1635166 is a single position in the genome, in or near the HERC2 gene. Published research associates it with left eye retinal fundus image self-supervised embedding endophenotype 116. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1635166 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1635166 come from?
GWAS Catalog, PLoS genetics 2024, PMID:38728357. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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