0 152319Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 181,219 European ancestry individuals, 43,861 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.1 higher; p = 3 × 10−13.
How common The A allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — in the 3′ untranslated region of HLA-F-AS1.
What each result means
A/ATwo copies of the version the research linked to Age at menopause. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Age at menopause. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Age at menopause. This is the starting point the study compared everyone against.
The Journal of clinical endocrinology and metabolism · 2021 · PMID 34050765
Questions about rs1628578
What is rs1628578?
rs1628578 is a single position in the genome, in or near the HLA-F-AS1 gene. Published research associates it with age at menopause. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1628578 linked to?
On MyGeneLog this position is linked to Age at Menopause. The research behind each link, and its sources, are set out on that condition page.
Does having rs1628578 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1628578 come from?
GWAS Catalog, The Journal of clinical endocrinology and metabolism 2021, PMID:34050765. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 152319Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Age at menopause (rs1628578). MyGeneLog™. https://www.mygenelog.com/variants/rs1628578