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Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256)

COL8A1 · rs1610263

Where this position leads

Condition: Celiac Disease

rs1610263 Condition: Celiac Disease Celiac Disease Condition rs1610263 rs1610263 COL8A1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0231 lower (95% confidence interval 0.016-0.03); p = 2 × 10−11.

How common The A allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 3, band 3q12.1 — in an intron of COL8A1.

What each result means

A/A Two copies of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is a smaller link than two copies.
T/T No copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). This is the starting point the study compared everyone against.
Source

Questions about rs1610263

What is rs1610263?

rs1610263 is a single position in the genome, in or near the COL8A1 gene. Published research associates it with forced expiratory volume in 1 second fev1 z score (ukb data field 20256). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1610263 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1610263 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1610263 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256) (rs1610263). MyGeneLog™. https://www.mygenelog.com/variants/rs1610263

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