Standard

Forced expiratory volume in 1 second (occupational environmental exposures interaction)

PDE4D · rs159497

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Forced expiratory volume in 1 second (occupational environmental exposures interaction) compared to the general population. (GWAS Catalog, J Allergy Clin Immunol 2015, PMID:25979521)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Forced expiratory volume in 1 second (occupational environmental exposures interaction). (GWAS Catalog, J Allergy Clin Immunol 2015, PMID:25979521)

T/T Published research associates this genotype with typical/baseline likelihood of Forced expiratory volume in 1 second (occupational environmental exposures interaction) — no copies of the reported risk allele. (GWAS Catalog, J Allergy Clin Immunol 2015, PMID:25979521)

Source

Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels

de Jong K, Vonk JM, Timens W, Bossé Y, Sin DD, Hao K, Kromhout H, Vermeulen R, Postma DS, Boezen HM

The Journal of allergy and clinical immunology · 2015 · PMID 25979521

Questions about rs159497

What is rs159497?

rs159497 is a single position in the genome, in or near the PDE4D gene. Published research associates it with forced expiratory volume in 1 second (occupational environmental exposures interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs159497 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs159497 come from?

GWAS Catalog, J Allergy Clin Immunol 2015, PMID:25979521. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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