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QT dynamics during exercise

NME7 · rs1591734

What the study found

Who was studied 28,449 European ancestry women, 24,412 European ancestry men.

The effect Each copy of the C allele shifted the measure 0.069 bpm higher (95% confidence interval 0.053-0.085); p = 4 × 10−20.

How common The C allele had a frequency of about 86% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of NME7.

What each result means

C/C Two copies of the version the research linked to QT dynamics during exercise. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to QT dynamics during exercise. That is a smaller link than two copies.
T/T No copy of the version the research linked to QT dynamics during exercise. This is the starting point the study compared everyone against.
Source

Questions about rs1591734

What is rs1591734?

rs1591734 is a single position in the genome, in or near the NME7 gene. Published research associates it with qt dynamics during exercise. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1591734 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1591734 come from?

GWAS Catalog, GWAS Catalog n.d., PMID:32527199. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

QT dynamics during exercise (rs1591734). MyGeneLog™. https://www.mygenelog.com/variants/rs1591734

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