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CD4 regulatory T cell %CD4+ T cell

RBM17 · rs1571025

What the study found

Who was studied 3,437 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.242 higher (95% confidence interval 0.18-0.31); p = 1 × 10−12.

How common The G allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 10, band 10p15.1 — in an intron of RBM17.

What each result means

A/A No copy of the version the research linked to CD4 regulatory T cell %CD4+ T cell. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to CD4 regulatory T cell %CD4+ T cell. That is a smaller link than two copies.
G/G Two copies of the version the research linked to CD4 regulatory T cell %CD4+ T cell. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1571025

What is rs1571025?

rs1571025 is a single position in the genome, in or near the RBM17 gene. Published research associates it with cd4 regulatory t cell %cd4+ t cell. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1571025 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1571025 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CD4 regulatory T cell %CD4+ T cell (rs1571025). MyGeneLog™. https://www.mygenelog.com/variants/rs1571025

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