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The effect
Each copy of the A allele carried 1.06 times the odds of Chronic obstructive pulmonary disease (95% confidence interval 1.04-1.08); p = 2 × 10−8.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 10, band 10q24.33 — in an intron of STN1.
What each result means
A/ATwo copies of the version the research linked to Chronic obstructive pulmonary disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Chronic obstructive pulmonary disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Chronic obstructive pulmonary disease. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30804561 · open access
Questions about rs1570221
What is rs1570221?
rs1570221 is a single position in the genome, in or near the STN1 gene. Published research associates it with chronic obstructive pulmonary disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1570221 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs1570221 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1570221 come from?
GWAS Catalog, Nature genetics 2019, PMID:30804561. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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