Sensitive

Coronary artery disease (MTAG)

near TBC1D1 · rs1565115

Where this position leads

Condition: Coronary Artery Disease

rs1565115 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs1565115 rs1565115 near TBC1D1

What the study found

Who was studied 310,368 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 5.73 z-score higher; p = 1 × 10−8.

How common The C allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 4, band 4p14 — in an intron of LINC02513.

What each result means

C/C Two copies of the version the research linked to Coronary artery disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Coronary artery disease (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Coronary artery disease (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs1565115

What is rs1565115?

rs1565115 is a single position in the genome, in or near the near TBC1D1 gene. Published research associates it with coronary artery disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1565115 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1565115 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1565115 come from?

GWAS Catalog, NPJ genomic medicine 2025, PMID:41022758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease (MTAG) (rs1565115). MyGeneLog™. https://www.mygenelog.com/variants/rs1565115

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