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Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.
The effect
Each copy of the T allele shifted the measure 0.0224 mg dl-1 higher (95% confidence interval 0.016-0.029); p = 1 × 10−11.
How common The T allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 4, band 4p16.3 — in an intron of GAK.
What each result means
C/CNo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2018 · PMID 30275531 · open access
Questions about rs1564282
What is rs1564282?
rs1564282 is a single position in the genome, in or near the GAK gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1564282 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
Does having rs1564282 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1564282 come from?
GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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