Who was studied 340,159 European ancestry individuals, 145,505 East Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0244 higher (95% confidence interval 0.019-0.029); p = 3 × 10−20.
Where it sits Chromosome 4, band 4q21.23 — in an intron of ARHGAP24.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Systolic blood pressure — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systolic blood pressure.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systolic blood pressure compared to the general population.
rs1563000 is a single position in the genome, in or near the ARHGAP24 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1563000 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs1563000 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1563000 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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