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Medication use (thyroid preparations)

RP11-89M16.1 · rs1561924

Where this position leads

Condition: Medication Use as a Genetic Trait

rs1561924 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs1561924 rs1561924 RP11-89M16.1

What the study found

Who was studied 24,832 European ancestry cases, 280,750 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0872 lower (95% confidence interval 0.06-0.114); p = 2 × 10−10.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — in an intron of LINC00824.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (thyroid preparations) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (thyroid preparations).
G/G Published research associates this genotype with typical/baseline likelihood of Medication use (thyroid preparations) — no copies of the reported risk allele.
Source

Questions about rs1561924

What is rs1561924?

rs1561924 is a single position in the genome, in or near the RP11-89M16.1 gene. Published research associates it with medication use (thyroid preparations). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1561924 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs1561924 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1561924 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (thyroid preparations) (rs1561924). MyGeneLog™. https://www.mygenelog.com/variants/rs1561924

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