Sensitive

Parkinson's disease

LINC01147 · rs1561758

Where this position leads

Condition: Parkinson's Disease

rs1561758 Condition: Parkinson's Disease Parkinson's Disease Condition rs1561758 rs1561758 LINC01147

What the study found

Who was studied 57,893 European ancestry cases, 1,505,102 European ancestry controls, 7,046 East Asian ancestry cases, 176,756 East Asian ancestry controls, 2,440 Hispanic or Latin American cases, 582,220 Hispanic or Latin American controls, 288 African ancestry cases, 193,985 African ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 9 × 10−10.

Where it sits Chromosome 14, band 14q31.3 — in an intron of LINC01147.

What each result means

C/C Two copies of the version the research linked to Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Parkinson's disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Parkinson's disease. This is the starting point the study compared everyone against.
Source

Questions about rs1561758

What is rs1561758?

rs1561758 is a single position in the genome, in or near the LINC01147 gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1561758 linked to?

On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1561758 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1561758 come from?

GWAS Catalog, Nature genetics 2024, PMID:38155330. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Parkinson's disease (rs1561758). MyGeneLog™. https://www.mygenelog.com/variants/rs1561758

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