Standard
Body mass index
POMC · rs1561288
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
Source
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
Graff M,
Ngwa JS,
Workalemahu T,
Homuth G,
Schipf S,
Teumer A,
Völzke H,
Wallaschofski H,
Abecasis GR,
Edward L,
Francesco C,
Sanna S
and 37 more — show all
Scheet P,
Schlessinger D,
Sidore C,
Xiao X,
Wang Z,
Chanock SJ,
Jacobs KB,
Hayes RB,
Hu F,
Van Dam RM,
Crout RJ,
Marazita ML,
Shaffer JR,
Atwood LD,
Fox CS,
Heard-Costa NL,
White C,
Choh AC,
Czerwinski SA,
Demerath EW,
Dyer TD,
Towne B,
Amin N,
Oostra BA,
Van Duijn CM,
Zillikens MC,
Esko T,
Nelis M,
Nikopensius T,
Metspalu A,
Strachan DP,
Monda K,
Qi L,
North KE,
Cupples LA,
Gordon-Larsen P,
Berndt SI
Human molecular genetics · 2013 · PMID 23669352
Questions about rs1561288
What is rs1561288?
rs1561288 is a single position in the genome, in or near the POMC gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1561288 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1561288 come from?
GWAS Catalog, Hum Mol Genet 2013, PMID:23669352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants