Sensitive

Schizophrenia

IGIP · rs156089

Where this position leads

Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk)

rs156089 Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk) Autism Spectrum Disorder and Schizo… Condition rs156089 rs156089 IGIP

What the study found

Who was studied 37,759 European ancestry cases, 7,509 African American cases, 1,234 Latino cases, 22,778 East Asian ancestry cases, 91,590 European ancestry controls, 8,337 African American controls, 3,090 Latino controls, 35,362 East Asian ancestry controls.

The effect Each copy of the C allele carried 1.05 times the odds of Schizophrenia (95% confidence interval 1.03-1.07); p = 2 × 10−8.

Where it sits Chromosome 5, band 5q31.3 — between genes, 13.4 kb from IGIP.

What each result means

C/C Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs156089

What is rs156089?

rs156089 is a single position in the genome, in or near the IGIP gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs156089 linked to?

On MyGeneLog this position is linked to Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk). The research behind each link, and its sources, are set out on that condition page.

Does having rs156089 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs156089 come from?

GWAS Catalog, Schizophrenia bulletin 2021, PMID:33169155. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Schizophrenia (rs156089). MyGeneLog™. https://www.mygenelog.com/variants/rs156089

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