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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,701 European ancestry individuals; replicated in 16,378 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−10.
How common The T allele had a frequency of about 61% in the people studied.
Where it sits Chromosome 15, band 15q23 — between genes, 12.3 kb from LARP6.
What each result means
C/CNo copy of the version the research linked to Proinsulin levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Proinsulin levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Proinsulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1549318 is a single position in the genome, in or near the LARP6 gene. Published research associates it with proinsulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1549318 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1549318 come from?
GWAS Catalog, Diabetes 2011, PMID:21873549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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