Standard

C-reactive protein

CCDC162P · rs1546721

Where this position leads

Condition: C-Reactive Protein Levels

rs1546721 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs1546721 rs1546721 CCDC162P

What the study found

Who was studied 353,466 European ancestry individuals, 83,025 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0122 lower (95% confidence interval 0.0079-0.0165); p = 3 × 10−8.

Where it sits Chromosome 6, band 6q21 — in an intron of CCDC162P.

What each result means

C/C Two copies of the version the research linked to C-reactive protein. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to C-reactive protein. That is a smaller link than two copies.
T/T No copy of the version the research linked to C-reactive protein. This is the starting point the study compared everyone against.
Source

Questions about rs1546721

What is rs1546721?

rs1546721 is a single position in the genome, in or near the CCDC162P gene. Published research associates it with c-reactive protein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1546721 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs1546721 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1546721 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-reactive protein (rs1546721). MyGeneLog™. https://www.mygenelog.com/variants/rs1546721

← See all variants