Standard

Homocysteine levels

DPEP1 · rs154657

Where this position leads

Condition: Homocysteine Levels

rs154657 Condition: Homocysteine Levels Homocysteine Levels Condition rs154657 rs154657 DPEP1

What the study found

Who was studied 44,147 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0963 higher (95% confidence interval 0.083-0.11); p = 2 × 10−43.

How common The A allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 16, band 16q24.3 — in a regulatory region of CHMP1A.

What each result means

A/A Two copies of the version the research linked to Homocysteine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Homocysteine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Homocysteine levels. This is the starting point the study compared everyone against.
Source

Questions about rs154657

What is rs154657?

rs154657 is a single position in the genome, in or near the DPEP1 gene. Published research associates it with homocysteine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs154657 linked to?

On MyGeneLog this position is linked to Homocysteine Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs154657 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs154657 come from?

GWAS Catalog, Am J Clin Nutr 2013, PMID:23824729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Homocysteine levels (rs154657). MyGeneLog™. https://www.mygenelog.com/variants/rs154657

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