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Gout vs asymptomatic hyperuricemia

PPM1K-DT · rs1545207

Where this position leads

Condition: Gout

rs1545207 Condition: Gout Gout Condition rs1545207 rs1545207 PPM1K-DT

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gout vs asymptomatic hyperuricemia compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gout vs asymptomatic hyperuricemia.
G/G Published research associates this genotype with typical/baseline likelihood of Gout vs asymptomatic hyperuricemia — no copies of the reported risk allele.
Source

Questions about rs1545207

What is rs1545207?

rs1545207 is a single position in the genome, in or near the PPM1K-DT gene. Published research associates it with gout vs asymptomatic hyperuricemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1545207 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs1545207 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1545207 come from?

GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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