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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 771 Japanese ancestry female cases, 76,625 Japanese ancestry female controls, 28,086 European ancestry cases, 546,291 European ancestry controls.
The effect
Each copy of the C allele carried 1.06 times the odds of Pelvic organ prolapse (95% confidence interval 1.041-1.08); p = 4 × 10−10.
Where it sits Chromosome 16, band 16q12.1 — between genes, 102.5 kb from HNRNPA1L3.
What each result means
C/CTwo copies of the version the research linked to Pelvic organ prolapse. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Pelvic organ prolapse. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Pelvic organ prolapse. This is the starting point the study compared everyone against.
Communications biology · 2024 · PMID 39349682 · open access
Questions about rs1544637
What is rs1544637?
rs1544637 is a single position in the genome, in or near the near HNRNPA1L3 gene. Published research associates it with pelvic organ prolapse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1544637 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1544637 come from?
GWAS Catalog, Communications biology 2024, PMID:39349682. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Pelvic organ prolapse (rs1544637). MyGeneLog™. https://www.mygenelog.com/variants/rs1544637