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Triglyceride levels

ANGPTL8 · rs1541924

What the study found

Who was studied 99,432 Admixed African or African ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0816 higher (95% confidence interval 0.065-0.098); p = 8 × 10−22.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — in an intron of ANGPTL8.

What each result means

C/C Two copies of the version the research linked to Triglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Triglyceride levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglyceride levels. This is the starting point the study compared everyone against.
Source

Questions about rs1541924

What is rs1541924?

rs1541924 is a single position in the genome, in or near the ANGPTL8 gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1541924 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1541924 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (rs1541924). MyGeneLog™. https://www.mygenelog.com/variants/rs1541924

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